OEHHA to Task the DART-IC with Cannabis Toxicity Evaluation


California’s Office of Environmental Health Hazard Assessment (OEHHA) has engaged the state’s Developmental and Reproductive Toxicant Identification Committee (DARTIC) of OEHHA’s Science Advisory Board to evaluate whether certain cannabis compounds, such as (marijuana), marijuana (cannabis) smoke, cannabis extracts, and Δ-9-Tetrahydrocannabinol (THC) has been shown to cause reproductive toxicity (developmental toxicity endpoint). Chemicals identified as reproductive toxicants by the DARTIC are added to the Proposition 65 list.
OEHHA will develop hazard identification materials on cannabis chemicals and is requesting scientific information relevant to whether they cause reproductive toxicity (developmental toxicity endpoint). The data call-in period will end at 5:00 p.m. on April 29, 2019. The committee meeting is tentatively planned for sometime in the Fall of 2019, but the date has not been announced.
The timing of the evaluation is interesting as the USDA has hinted at possibly loosening restrictions for certain cannabidiol extracts in food or dietary supplements.
The departure of Commissioner Scott Gotlieb from his post may not have much of an impact going forward. Recently Commissioner Gotlieb announced the formation of a working group to develop rules that would permit the use of certain extracts from hemp in food or dietary supplements and indicated that a public hearing was being planned to discuss how some uses of cannabidiol in food and dietary supplements might be legalized.
Dart-IC’s upcoming evaluation of cannabis compounds may have a profound impact on the cannabis industry if the compounds are found to cause developmental toxicity.
Such a finding would cause Canibus providers to post “Clear and reasonable warnings along the lines of the alcohol warnings for pregnant women.

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