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Chemicals Under Consideration, Recently Listed or Modified Under Proposition 65

 

 

 

Chemicals Under Consideration


Chemical

CAS No

Authoritative Body

Date

End Point

Status

Clomiphene Citrate

911-45-5

FDA - Formally Re- quired to be Labeled or Identified

4/6/2013

Cancer

Request for information public comments dead- line: 5/6/2013. Listed effective 5/24/2013.

N-Methyl-N-nitroso-1-oc- tanamine

34423-54-6

SQE - Carcinogen Identification Commit- tee

3/22/2013

Cancer

Request for information public comment dead- line: 5/21/2013

N-Methyl-N-nitroso-1-de- canamine

75881-22-0

SQE - Carcinogen Identification Commit- tee

3/22/2013

Cancer

Request for Information public comment dead- line: 5/21/2013

N-Methyl-N-nitroso-1-do- decanamine

55090-44-3

SQE - Carcinogen Identification Commit- tee

3/22/2013

Cancer

Request for Information public comment dead- line: 5/21/2013

N-Methyl-N-nitroso-1-tet- radecanamine

75881-20-8

SQE - Carcinogen Identification Commit- tee

3/22/2013

Cancer

Request for Information public comment deadline

5/21/2013

Coal Emissions

N/A

IARC

3/15/2013

Cancer

Request for Information public comments due

5/14/2013

Methyl Isobutyl Ketone

108-10-1

EPA

3/15/2013

Developmental

Toxicity

Request for Information public comments due

5/14/2013

Trichloroethylene

79-01-6

EPA

3/15/2013

Male reproduc- tive and devel- opmental toxicity

Request for Information public comments due

5/14/2013


 


Chemical

CAS No

Authoritative

Body

Date

End Point

Status

Hydrogen Cyanide and Cyanide Salts

- -

U.S. EPA

3/22/2013

Male Repro- ductive Tox- icity

Request for information: 5/13/2011;

Notice of Intent to List: 3/22/2013

Bisphenol A

80-05-7

NTP

1/25/2013

Developmen- tal toxicity

Issued Notice of Intent to List, Pro- posed MADL and Request for Infor- mation. Public comment period extended to 4/10/2013. Listed on April 11, 2013. Preliminary Injunc- tion halting listing process and delisting BPA issued 4/19/2013.

Styrene

100-42-5

NTP

1/4/2013

Cancer

Re-issue Notice of Intent to List via Labor Code mechanism based on National Toxicology Program’s listing in the Report on Carcinogens and finding of sufficient evidence of carci- nogenicity in experimental animals. Proposal withdrawn - 2/15/2013.

Actinomycin D

50-76-0

FDA

1/4/2013

Cancer

Issue Notice of Intent to Change Ba- sis for Listing to Formally Required to be Labeled or Identified as Causing Cancer based on the U.S. FDA-ap- proved cancer warning.

Butyl Benzyl Phthalate

75321-20-9

SQE - Carcino- gen Identification Committee

11/26/2012

Cancer

OEHHA to prepare hazard identifica- tion materials for review by the Car- cinogen Identification Committee at a future meeting to be announced. Public comments posted: 2/5/2013

Deltamethrin

52918-63-5

DART

7/13/2011

Developmen- tal/ Repro- ductive toxicant

Pending. Data Call-In and public comment period closed 3/20/2012. Public Comments Received. Hazard Identification Materials were released

10/12/2012. DART Committee de- clined to list at developmental, male and female endpoints -

3/18/2013.


Proposed or Recently Modified NSRLs and MADLS


Chemical

CAS No

Date

Referred

By

Previous Level

New Level

Bisphenol A

80-05-7

1/25/2013

NTP

None

290 micrograms per day. Public comment period extended to 4/10/2013.

Chromium (hexava- lent compounds)

18540-29-9

11/1/2012

US EPA

Section 25707(b)(4) refer- ence CR6 poses no sig- nificant risk when ingested.

Deleted reference as pos- ing no significant risk

when ingested. Amend- ment takes effect

11/1/2012.

Bromoethane

74-96-4

8/31/2012

NTP

None. NSRL proposed. Public comment period ended 10/15/2012. NSRL took effect 1/16/2013.

96 ug/day

Sulfur Dioxide

7446-09-5

6/28/2012

DART

None. MADL proposed. Public comment posted

8/28/2012

Original proposal - 220 ug/day. Amended pro- posed MADL 10,000 ug/day

Benzyl Butyl Phtha- late (BBP)

85-68-7

6/1/2012

NTP

None. MADL proposed.

1,200 ug/day Oral. Public comments posted

2/5/2013.

Tris(1,3-dichloro-2- propyl) phosphate (TDCPP)

13674-87-8

6/1/2012

CIC

None. NSRL proposed. Ad- opted 10/9/2012.

5.4 ug/day

Chloroform

67-66-3

5/18/2012

DART

None. MADL proposed. Proposed MADL with- drawn by OEHHA on

1/10/2013

600 ug/day

Imazalil

35554-44-0

4/25/2012

US EPA

None. NSRL adopted.

11 ug/day

Polychlorinated bi- phenyls (PCBs)

27323-18-8

4/13/2012

US EPA

NSRL: 0.09 ug/day Public comment period extended on 5/25/2012. Proposal withdrawn on 12/21/2012.

NSRL proposed 0.35 ug/day; MADL proposed for 2.3 ug/day – both levels limited to food chain expo- sures.

Methanol

67-56-1

3/16/2012

NTP

None. Proposed MADLs:

47,000 ug/day (Inhalation)

and 23,000 ug/day (Oral)

47,000 ug/day (Inhalation) and 23,000 ug/day (Oral). Comment period was ex- tended to June 25, 2012. Public meeting held May 7. Adopted 4/18/2013, effec- tive 7/1/2013.


Recently Listed Chemicals

 

Chemical

 

CAS No

 

Referred By

 

Listing Date

 

End Point

Clomiphene Citrate

50-41-9

FDA

5/24/2013

Cancer

C.I. Disperse Yellow 3

2832-40-8

CIC

2/8/2013

Cancer

2,6-Dimethyl-N-Nitrosomorpho- line (2,6-DNN)

1456-28-5)

CIC

2/8/2013

Cancer

Alpha-Methylstyrene

98-83-9

IARC

11/2/2012

Cancer

1,3-Dinitropyrene

75321-20-9

IARC

11/2/2012

Cancer

 

Isopyrazam

 

881685-58-1

 

US EPA

 

7/24/2012

 

Cancer

 

3,3',4,4'-Tetrachloroazobenzene

 

14047-09-7

 

NTP

 

7/24/2012

 

Cancer

 

Benzophenone

 

119-61-9

 

IARC

 

6/22/2012

 

Cancer

 

Coconut oil diethanolamine con- densate (cocamide dietha- nolamine)

 

 

68603-42-9

 

 

IARC

 

 

6/22/2012

 

 

Cancer

 

Diethanolamine

 

111-42-2

 

IARC

 

6/22/2012

 

Cancer

 

2-Methylimidazole

 

693-98-1

 

IARC

 

6/22/2012

 

Cancer

 

Methanol

 

67-56-1

 

NTP

 

3/16/2012

 

Developmental


Recently Delisted Proposition 65 Chemicals


 

Chemical

 

CAS No

 

Referred By

 

Delist Date

 

End Point

Bisphenol A

80-05-7

NTP

4/19/2013

Developmental

 

Chloramphenicol

 

56-75-7

 

IARC

 

1/4/2013

 

Cancer

 

Dienestrol

84-17-3

 

IARC

1/4/2013

Cancer

 

Proposition 65 Chemicals Removed From Consideration 

 

Chemical

 

CAS No

 

Referred By

 

Removal Date

 

Bleomycins

 

N/A

 

Removed from consideration for listing via the Labor

Code mechanism.

 

1/4/2013

 

Chlorophenoxy herbicides

 

N/A

Removed from consideration for listing via the Labor

Code mechanism.

 

1/4/2013

 

Diesel fuel, marine

 

N/A

Removed from consideration for listing via the Labor

Code mechanism.

 

1/4/2013

 

Progestins

N/A

Removed from consideration for listing via the Labor

Code mechanism.

 

1/4/2013

 

 

 

Styrene

 

 

 

100-42-5

Re-issue Notice of Intent to List via Labor Code mecha- nism based on National Toxicology Program’s listing in the Report on Carcinogens and finding of sufficient evi- dence of carcinogenicity in experimental animals. Pro- posal withdrawn.

 

 

 

1/4/2013

Vinyl acetate

108-05-4

Removed from consideration for listing via the Labor

Code mechanism.

1/4/2013

 

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